In her artistic practice, Delphine Wigger explores themes of sexuality, nostalgia, feminism, and childhood/adolescence. Her work is often rooted in deeply personal source material: diary entries, notes, and drawings from her teenage years, which she incorporates into her paintings or renders visible as textual fragments. These texts function not only as traces of memory, but as emotional markers that oscillate between intimacy and exposure.

The visual motifs in her work frequently originate from sketchbooks of her early youth or from objects that held particular significance during her childhood. Through the process of painting, these memories are transformed, re-appropriated, and translated into the present. Central to her practice is a recurring tension between vulnerability and empowerment, and between personal narrative and collective experience.

Alongside painting, she sometimes translates these motifs into other media such as photography, installation, or bronze sculpture.